Intermittent hypoxia and respiratory plasticity in humans and other animals: does exposure to intermittent hypoxia promote or mitigate sleep apnoea?
نویسندگان
چکیده
منابع مشابه
Cardiovascular and Respiratory Effects of Exposure to Experimental Models of Obstructive Sleep Apnoea-related Intermittent Hypoxia
Obstructive sleep apnoea (OSA) is a common chronic condition characterised by repetitive nocturnal upper airway collapse that evokes intermittent hypoxia (IH). Although animal research has demonstrated a causal relationship between IH and cardiovascular disease there is a relative paucity of human research. Using a variety of different models of OSA we investigated the effects of IH on respirat...
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Mitchell, Gordon S., Tracy L. Baker, Steven A. Nanda, David D. Fuller, Andrea G. Zabka, Brad A. Hodgeman, Ryan W. Bavis, Kenneth J. Mack, and E. B. Olson, Jr. Invited Review: Intermittent hypoxia and respiratory plasticity. J Appl Physiol 90: 2466–2475, 2001.— Intermittent hypoxia elicits long-term facilitation (LTF), a persistent augmentation (hours) of respiratory motor output. Considerable r...
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physiology, especially those papers emphasizing adaptive and integrative mechanisms. It is published 12 times a publishes original papers that deal with diverse area of research in applied
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Obstructive sleep apnoea syndrome (OSAS) is associated with severe cerebro-cardiovascular morbidity and mortality. It is an independent risk factor for atherosclerosis, arterial thrombosis and metabolic syndrome, and recently has been associated with an increased incidence of cancer and death. A causal link between OSAS and atherosclerosis has been partially established. Recent research on athe...
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In recent years, it has become clear that brief, repeated presentations of hypoxia [i.e., acute intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in certain cases of neurologic dysfunction. This hypothesis derives from a series of studies in animal models and human subjects performed over the past 35 yr. In 1980, Millhorn et al. (Millhorn DE, Eldridge...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2009
ISSN: 0958-0670
DOI: 10.1113/expphysiol.2008.045153